Anti-fat bias, or fatphobia, is the intense hatred or fear of people living in larger bodies, and it contributes to the popularity of medications like naltrexone. You should always consult your doctor, and naltrexone side effects your medical team, before taking medication for weight loss. Trying to lose weight quickly by taking Revia or other medications can cause a host of side effects and health risks. Naltrexone belongs to a group of drugs called opioid antagonists.

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Overall, the certainty of evidence for gastrointestinal (GI) adverse effects (AEs) ranged from low to moderate, with highest consistency among incretin-based therapies. Following the quality appraisal (Table 3 and Table 4), a narrative GRADE-style summary of evidence certainty for GI AEs across all included studies is presented in Table 5. The certainty of evidence ranged from low to moderate, reflecting strong consistency among incretin-based therapies but variable reporting standards and smaller sample sizes in other drug classes. Verifying the relevance of studies to the review topic involved a structured assessment of each article’s methodological what is alcoholism quality and risk of bias (RoB) using established appraisal tools.
- It’s not known whether naltrexone should be taken during pregnancy.
- The rationale behind combining naltrexone and B12 for weight loss rests on the idea of a synergistic effect.
- Regularly monitoring your energy levels and practicing self-care routines can empower you to overcome this hurdle.
- By blocking the pleasurable effects of these substances, Naltrexone helped individuals reduce cravings and maintain sobriety.
- Individual needs will vary, and it’s important to discuss personal circumstances with our own practitioner and treatment team.
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For this medication to be most effective, you should attend any counseling or support groups that your care team recommends. Do not try to overcome the effects of the medication by taking large amounts of opioids or by drinking large amounts of alcohol. Also, you may be more sensitive to lower doses of opioids after you stop taking this medication.
Less Common but Serious Side Effects
In many cases, side effects such as dizziness and digestive problems go away within a few hours to days of starting naltrexone treatment. But how long side effects last can vary from person to person. Naltrexone is a generic prescription drug used to treat certain substance use disorders. Naltrexone oral tablet does not come in any brand-name versions.
- Nausea occurred in 44.2% vs. 17.4%, diarrhea 31.5% vs. 15.9%, vomiting 24.8% vs. 6.6%, and constipation 23.4% vs. 9.5%.
- The dose of this medicine will be different for different patients.
- Naltrexone is also commonly used to treat weight loss, either by itself or in combination with Wellbutrin/bupropion.
- Vitamin B12, or cobalamin, is a crucial nutrient involved in numerous metabolic processes, including DNA synthesis, red blood cell formation, and nerve function.
Gastrointestinal Adverse Effects of Anti-Obesity Medications in Non-Diabetic Adults: A Systematic Review

Always talk to your healthcare provider about the right dosage for you and any possible side effects. Naltrexone can be a useful part of your weight loss strategy when you also focus on a balanced diet, regular exercise, and making changes in your lifestyle. Take care of your health as you consider how naltrexone can support your weight loss efforts.
